The deadline for applications is July 10th 2014

We are looking for a motivated candidate for a research project described
below.

Position is at the Institute of Genetics and Biophysics - National Research
Council in Napoli, Italy  http://www.igb.cnr.it/
Deadline for applications is 10/07/2014

BACKGROUND -  The understanding of genetic variation is essential to decode
traces that evolution has left in our genomes and whole-genome sequence
data now allow us to do interpret these signals at a resolution never
possible before. Adaptive processes in humans have left signature in the
genome and information about sites putatively under positive selection in
human is now available.Next challenge is to combine this information with
functional interpretation to understand the environmental pressure that
drove
the adaptation and the underlying molecular mechanisms at cellular level.

RESEARCH PROJECT - This project aims to study functional consequences of a
mutation in a gene showing evidences for positive selection in Asians and
Europeans. This gene is implicated in the formation of the skin lipid
barrier and regulated by UV radiation. Alterations of the gene sequence
cause severe forms of skin diseases.
This project will clarify key molecular mechanisms of interaction of humans
with the environment and advance our understanding of the role of
environmental adaptation in modern diseases. Project includes both wet
laboratory experiments (40% ) and bioinformatics analyses (60%) and a
mandatory work experience abroad.

ELIGIBILITY  - Candidates with a master degree either in biology/medicine
or  informatics/mathematics/physics/engineer are equally eligible and in
each case they should be willing to do both wet laboratory and
computational analyses.

SELECTION CRITERIA - The successful applicant will be selected on
documented theoretical and experimental knowledge relevant for the area of
study, knowledge of scientific theory and method, analytical skills,
personal motivation and team working skills. Well-developed English
language skills are required. The applicants are encouraged to provide
supporting documents that substantiate qualifications, e.g.,
knowledge, skills, abilities and experience. Experience with programming
languages is a plus. References and interviews will be used to assess
qualifications of the applicants.

INFORMATION - We encourage to discuss your application before submitting.
Please contact vincenza.colonna@igb.cnr.it.
For more information visit: http://goo.gl/axpzzw and http://www.igb.cnr.it/

APPLICATIONS
Applications should be submitted to vincenza.colonna@igb.cnr.it and should
include:
1. Cover letter
2. CV with information about your:
a) Degrees and education
b) Job experience
c) Independent project �V Masters project title and brief description
d) Language skills
e) References�V name and e-mail addresses of 2�V3 reference persons
3. Research plan �V this should be a personal statement motivating why
   you are applying for this position (maximum 2 pages)
4. Other documents �V other documents you may wish to provide

The deadline for applications is July 10th 2014

would you like to know about the most amazing project ever?
http://www.igb.cnr.it/obilab

interested in Life Science and/or Mathematics? visit http://www.bmtl.it/

Vincenza Colonna
Consiglio Nazionale delle Ricerche
Istituto di Genetica e Biofisica "Adriano Buzzati-Traverso"
piano 1, stanza 20
via Pietro Castellino 111 - 80131 Napoli - IT

tel +39 081 6132 254
fax +39 081 6132 706
skype enza.colonna
email vincenza.colonna@igb.cnr.it

http://www.igb.cnr.it/index.php?id=90&staff_detail=colonna
http://scholar.google.co.uk/citations?user=ufP1EYgAAAAJ&hl=en&oi=ao

Visiting Scientist
The Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton  Cambs. CB10 1SA  UK

email cv1@sanger.ac.uk

vincenza colonna